Back

STI- Senarios

Scenario:
You are in the Emergency Department. A patient (male or female, age 25–40) presents worried about possible HIV exposure after recent sexual contact.
Your task:

  1. Take a relevant sexual history.
  2. Assess risk of HIV transmission.
  3. Explain investigations and management, including HIV post-exposure prophylaxis (PEP).
  4. Address concerns and provide safety-netting.

You are not expected to perform a physical exam.


🔶 1. Introduction and Communication

Approach:

  • Introduce yourself, confirm identity.
  • Ensure privacy and confidentiality.
  • Ask permission to take a sensitive history.
  • Use open, non-judgmental language.

“I understand this is a sensitive topic, but I’ll ask a few questions to understand your situation and discuss how best to help you.”


🔶 2. History Taking Framework

A. Presenting Concern

  • “Can you tell me what has brought you in today?”
  • “What specifically worries you about HIV?”

B. Exposure Details

  • Type of sexual contact: vaginal, anal, oral.
  • Use of protection (condoms? consistent?).
  • Timing of exposure (crucial for PEP window ≤72 h).
  • Partner’s status:
    • Known HIV-positive?
    • Unknown? From high-prevalence area?
    • IV drug user / sex worker?

“Was the partner’s HIV status known to you?”
“When did this sexual contact occur?”
“Was a condom used throughout?”

C. Other Risk Factors

  • Multiple partners / new partner.
  • MSM (men who have sex with men).
  • Drug use, especially injection.
  • History of STIs, blood transfusions, tattoos, etc.

D. Symptoms

  • Current symptoms of acute HIV (usually not relevant for <2 weeks exposure): fever, rash, sore throat, lymphadenopathy.
  • Other STI symptoms: discharge, ulcers, dysuria.

E. Past History

  • Past STIs, HIV tests, vaccinations (HBV, HPV).
  • Medication allergies.
  • Relevant medical history.

F. Social History

  • Occupation (healthcare worker?).
  • Living situation, partner, contraception.
  • Emotional state, support, mental health.

🔶 3. Risk Assessment

Summarise back to the patient:

“So, you had unprotected vaginal/anal sex with a partner of unknown status about 36 hours ago — that helps us assess your risk.”

Approximate HIV transmission risks per exposure:

Exposure TypeRisk (per 10,000 exposures)
Receptive anal sex138
Insertive anal sex11
Receptive vaginal sex8
Insertive vaginal sex4
Oral sex<1

🔶 4. Management Plan

A. HIV Post-Exposure Prophylaxis (PEP)

  • Indication: Within 72 hours of significant exposure to potentially infected source.
  • Regimen (UK 2025):
    • Tenofovir disoproxil / emtricitabine (Truvada)
    • + Dolutegravir (Tivicay)
    • Duration: 28 days.
  • Baseline tests:
    • HIV, Hep B & C, syphilis, pregnancy (if relevant), renal/liver function.
  • Follow-up:
    • HIV tests at baseline, 4 weeks, 12 weeks, and 24 weeks.
    • Sexual health clinic follow-up within 24–48 hours.

“If we start PEP today, it should ideally be taken within 72 hours of exposure and continued for 28 days.”

B. Post-Exposure Vaccination / Prophylaxis

  • Hepatitis B: offer vaccine ± immunoglobulin if not immune.
  • Other STIs: screen and treat as indicated.

C. Advice & Counselling

  • Avoid unprotected sex until follow-up (GUM clinic) confirms negative status.
  • Adherence and side effects of PEP.
  • Emotional support, referral to GUM Clinic.
  • Safe sex practices.


🔶 5. Closing the Station

Summarise:

  • Restate plan clearly.
  • Check understanding and concerns.

“So, today we’ll do baseline blood tests, and refer you to the sexual health clinic. We’ll support you through the follow-up process. How does that sound?”

Dr Mehdi Hassan Teeli
Clinical Director & Consultant in Emergency Medicine
(University Teaching Hospitals of East Lancashire NHS Trust)
Honorary Senior Lecturer of the University of Central Lancashire
CESR Lead Emergency Department 
C0-Chair portfolio pathway(CESR) at The Royal College of Emergency Medicine.